"Broad bean allergy disease" or "G6PD deficiency"

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"Broad bean allergy" or "G6PD deficiency" is that the body has lower levels of the enzyme G6PD than normal people. Which this type of enzyme is found in red blood cells Has the function of neutralizing free radicals. Stabilize red blood cells And prevent the red blood cells easily broken down

Cause of the disease

G6PD deficiency is a genetic disease. In Thailand, about 15% of males are transmitted from mother to son and about 3-4% of females are found. And men will get the disease Some people did not even realize they had this disease. Because screening was not performed at birth

Rupture of red blood cells Caused by the body's exposure Or some medications, such as broad beans, which contain a lot of antioxidants Especially fresh broad bean Will cause red blood cells to break more easily than eating cooked broad beans.

Exposure to certain drugs, such as certain NSAIDs, aspirin, certain antibiotics such as sulfa or nitrofurantoin, some antimalarial drugs such as quinine or quinidine.

Eating cherries, blueberries, some yogurts with nuts, red wine, and getting a bad smell.

If the patient is not eating forbidden food Or the drugs mentioned above Without any symptoms, it is important to know what foods and drugs to avoid. To prevent symptoms

Symptoms in children

Newborns have yellow eyes, with 1 in 3 children who need phototherapy. If the child is found to have jaundice, yellow eyes, the doctor will draw blood to look at the enzyme G6PD, which will tell from that time if the child has the disease.

Adult symptoms
Patients will have symptoms when receiving the drug. Or prohibited substances Because the person did not know before that the enzyme G6PD deficiency when red blood cells are broken Patients will have pale symptoms. Feeling tired and exhausted, with symptoms 1-2 days after exposure to prohibited substances. In addition, the urine will turn coke or fish sauce color. Due to hemolysis Resulting in kidney precipitation And discolored urine In which if you have this symptom, you should immediately come see a doctor

Treatment

This is because G6PD deficiency is not a dangerous disease. If the patient has not received the substance Or prohibited food Therefore there is no need to use drug treatment Or be cured

Treatment is therefore a supportive treatment. In the event that the patient has symptoms of fatigue, dizziness, fainting, coke colored urine. When you get to the hospital The doctor will give you a saline solution. To excrete coke from the body quickly After that, the red blood cells will stop breaking within 7-10 days.

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